Protein BEX1 also known as brain-expressed X-linked protein 1 is a protein that in humans is encoded by the BEX1gene.[5] BEX1 is a part of the BEX gene family well conserved in mammals. It is expressed in a wide range of tissues.[6] BEX proteins have connections to cancer and their direct functions are not fully understood. BEX1 is suggested to act as a tumor suppressant in certain situations.[6]
Further reading
Foltz G, Ryu GY, Yoon JG, et al. (2006). "Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma". Cancer Res. 66 (13): 6665–74. doi:10.1158/0008-5472.CAN-05-4453. PMID 16818640.
Alvarez E, Zhou W, Witta SE, Freed CR (2005). "Characterization of the Bex gene family in humans, mice, and rats". Gene. 357 (1): 18–28. doi:10.1016/j.gene.2005.05.012. PMID 15958283.
Quentmeier H, Tonelli R, Geffers R, et al. (2005). "Expression of BEX1 in acute myeloid leukemia with MLL rearrangements". Leukemia. 19 (8): 1488–9. doi:10.1038/sj.leu.2403820. PMID 15920485.
Baldisseri DM, Margolis JW, Weber DJ, et al. (2002). "Olfactory marker protein (OMP) exhibits a beta-clam fold in solution: implications for target peptide interaction and olfactory signal transduction". J. Mol. Biol. 319 (3): 823–37. doi:10.1016/S0022-2836(02)00282-6. PMID 12054873.
