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Naftopidil

Naftopidil ( INN , marketed under the brand name Flivas ) is a drug used in benign prostatic hyperplasia which acts as a selective α 1 -adrenergic receptor antagonist or alpha-1...

Naftopidil

Naftopidil (INN, marketed under the brand name Flivas) is a drug used in benign prostatic hyperplasia which acts as a selectiveα-adrenergic receptorantagonist or alpha-1 blocker.[1]

Synthesis

The reaction of 1-naphthol (1) with epichlorohydrin (2) in the presence of alkali gives the epoxide (3). Alkylation of the piperazine derivative (4) yields naftopidil.[2][3][4]

See also

สรุปเนื้อหา

ข้อมูลสำคัญจากบทความ

ข้อมูลสำคัญเกี่ยวกับ Naftopidil

Naftopidil ( INN , marketed under the brand name Flivas ) is a drug used in benign prostatic hyperplasia which acts as a selective α 1 -adrenergic receptor antagonist or alpha-1...

Synthesis

The reaction of 1-naphthol (1) with epichlorohydrin (2) in the presence of alkali gives the epoxide (3). Alkylation of the piperazine derivative (4) yields naftopidil. [ 2 ] [ 3 ] [ 4 ]